Guide to Microscopy about Cellular Ploidy Variation

Good morning

My name is Matheus, I’m starting out in the area of image analysis and I would like to develop an analysis and identification of polyploid cells in histological slides stained in HE and also with fluorescence.

I would like to know if there was any guide that highlights how to identify and characterize polyploid and multinucleated cells in slides observed using conventional or fluorescence microscopy?

Thanks a lot for the help.