Multiplex system

Dear all,
I’m currently exploring multiplex proteomic imaging platforms and I’d love to get your feedback or experiences with machines like COMET, PhenoCycler, and MACSIMA.

  • What are the pros and cons of these systems from your perspective?
  • How do they perform in terms of throughput, validation antibodies, speed, resolution, reproducibility, and ease of use?
  • Are there any specific challenges you’ve encountered with these machines?

I’m particularly interested in hearing from users who have tested or regularly use these technologies for high-dimensional proteomic analysis.
Best,