# Multiplex system

**URL:** <https://forum.microlist.org/t/multiplex-system/2925>\
**Category:** Hardware\
**Created:** [December 17, 2024, 3:26pm UTC](https://forum.microlist.org/t/multiplex-system/2925 "2024-12-17T15:26:02Z")\
**Posts on this page:** 1\
**Page:** 1

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**Author:** ![Alex.h](https://avatars.discourse-cdn.com/v4/letter/a/dec6dc/32.png) [@Alex.h](https://forum.microlist.org/u/Alex.h)\
**Post date:** [December 17, 2024, 3:26pm UTC](https://forum.microlist.org/t/multiplex-system/2925/1 "2024-12-17T15:26:02Z")

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Dear all,  
I’m currently exploring multiplex proteomic imaging platforms and I’d love to get your feedback or experiences with machines like **COMET** , **PhenoCycler** , and **MACSIMA**.

- What are the pros and cons of these systems from your perspective?
- How do they perform in terms of throughput, validation antibodies, speed, resolution, reproducibility, and ease of use?
- Are there any specific challenges you’ve encountered with these machines?

I’m particularly interested in hearing from users who have tested or regularly use these technologies for high-dimensional proteomic analysis.  
Best,